BFSCI Publications

Baron, Margaret, M.D.- Ph.D.
Fraser, S.T., Isern, J. and Baron, M.H.  (2007) Maturation and enucleation of primitive erythroblasts is accompanied by changes in cell surface antigen expression patterns during mouse embryogenesis. Blood 109: 343-352.  First Edition Paper, August 29, 2006; DOI 10.1182/blood-2006-03-006569.

Haremaki, T., Fraser, S.T., Kuo, Y.-M., Baron, M.H., and Weinstein, D.C. (2007) Vertebrate Ctr1 coordinates morphogenesis and progenitor cell fate and regulates embryonic stem cell differentiation. Proc. Natl. Acad. Sci. U.S.A. 104: 12029-12034.  Early Edition, 10.1073_pnas0701413104.

Willey, S., Ayuso-Sacido, A., Zhang, H., Fraser, S. T., Sahr, K. E., Adlam, M. J., Kyba, M., Daley, G. Q., Keller, G., and Baron, M. H. (2006). Acceleration of mesoderm development and expansion of hematopoietic progenitors in differentiating ES cells by the mouse Mix-like homeodomain transcription factor. Blood 107, 3122-3130.

Bieker, James, Ph.D.
M. P. Frontelo*, D. Manwani*, M. Galdass, H. Karsunky, F. Lohmann, P. G. Gallagher, and J. J. Bieker, Novel role for EKLF in megakaryocyte lineage commitment, Blood 110, 3871-3880 (2007). [*co-first authors]

Manwani, D., Galdass, M., and Bieker, J. J., Altered Regulation of Beta-like Globin Genes by a Redesigned Erythroid Transcription Factor, Experimental Hematology, 35, 39-47 (2007)

Adelman, C. A., Chattopadhyay, S., and Bieker, J. J. (2002). The BMP/BMPR/Smad pathway directs expression of the erythroid-specific EKLF and GATA1 transcription factors during embryoid body differentiation in serum-free media. Development 129, 539-549.

Frenette, Paul, M.D.
Katayama, Y., Battista, M., Kao, W. M., Hidalgo, A., Peired, A. J., Thomas, S. A., and Frenette, P. S. (2006). Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow. Cell 124, 407-421.

Hidalgo, A., and Frenette, P. S. (2005). Enforced fucosylation of neonatal CD34+ cells generates selectin ligands that enhance the initial interactions with microvessels but not homing to bone marrow. Blood 105, 567-575.

Germano, Isabelle, M.D.
Uzzaman, M., Benveniste, R. J., Keller, G., and Germano, I. M. (2005). Embryonic stem cell-derived astrocytes: a novel gene therapy vector for brain tumors. Neurosurg Focus 19, E6.

Ghaffari, Saghi, M.D.- Ph.D.
Marinkovic D., Zhang X., Yalcin S., Brugnara C., Huber T., and S. Ghaffari. Foxo3 is required for the regulation of oxidative stress in erythropoiesis, Journal of Clinical Investigation, 117 (8): 2133-2144,2007 (this paper is subject of discussion of Commentary: JCI, 107 (8): 2075-2077, 2007).

Yalcin S, Zhang X., Luciano J.P., Marinkovic D., Kumar Mungamuri S., Sarkar A., Vercherat C., Taneja R. and S. Ghaffari. Foxo3 Regulates Hematopoietic Stem and Progenitor Cell Fate via ATM-Mediated Modulation of Oxidative Stress (submitted, 2007).

Zhao W., Kitidis C., Fleming M.D, Lodish H.F. and S. Ghaffari. Erythropoietin stimulates phosphorylation and activation of GATA-1 via the PI3-kinase-AKT signaling pathway. Blood 107 (3): 907-915, 2006 (this paper is subject of discussion of Inside Blood: Blood: 107 (3): 851-85).

Huntley, George W., Ph.D.
Nagy, V., Bozdagi, O., Matynia, A., Balcerzyk, M., Okulski, P., Dzwonek, J., Costa, R. M., Silva, A. J., Kaczmarek, L., and Huntley, G. W. (2006). Matrix metalloproteinase-9 is required for hippocampal late-phase long-term potentiation and memory. J Neurosci 26, 1923-1934.

Brock, J. H., Elste, A., and Huntley, G. W. (2004). Distribution and injury-induced plasticity of cadherins in relationship to identified synaptic circuitry in adult rat spinal cord. J Neurosci 24, 8806-8817.

Krauss, Robert, Ph.D.
Zhang, W., J.-S. Kang, F. Cole, M.-J. Yi and R.S. Krauss. (2006). Cdo functions at multiple points in the Sonic Hedgehog pathway, and Cdo-deficient mice accurately model human holoprosencephaly. Dev. Cell 10:657-665.

Takaesu, G., J.-S. Kang, G.-U. Bae, M.-J. Yi, C.M. Lee, E.P. Reddy and R.S. Krauss. (2006). Activation of p38a/b MAPK in myogenesis via binding of the scaffold protein JLP to the cell surface protein Cdo. J. Cell Biol. 175:383-388.

Lemischka, Ihor, Ph.D., Director
Ivanova N.B., Dimos J.T., Schaniel C., Hackney J.A., Moore K.A., and Lemischka I.R. (2002) A stem cell molecular signature. Science 298: 601-604.

Phillips, R.L., Ernst, R.E., Brunk, B., Ivanova, N., Mahan, M.A., Deanehan, J.K., Moore, K.A., Overton, G.C., Lemischka, I.R. (2000) The Genetic Program of Hematopoietic Stem Cells. Science 288:1635-1640.

John (Xiajun) Li, Ph.D.
Li, X. , Youngson, N., Zhou, F., Ito, M., Leder, P. and Ferguson-Smith, A. A maternal zygotic effect gene Zfp57 maintains both maternal and paternal imprints. (manuscript)

Li, X. and Leder, P. (2007). Identifying genes preferentially expressed in undifferentiated embryonic stem cells. BMC Cell Biology 8: 37.

Lin, Riegh-Yi, Ph.D.
Lin, R.-Y. (2007) New insights into thyroid stem cells. Thyroid 17(10), 1019-1023

Lu, M. and Lin, R.-Y. (2007) Thyroid-stimulating hormone stimulates adipogenesis in mouse embryonic stem cells. J. Endocrinology, Epub ahead of print

Arufe, M.C., Lu, M., Kubo, A., Keller, G., Davies, T. F. and Lin, R.-Y. (2006) Directed differentiation of mouse embryonic stem cells into thyroid follicular cells. Endocrinology 147(6): 3007-3015

Merad, Miriam, M.D.- Ph.D.
Ginhoux, F., Tacke, F., Angeli, V., Bogunovic, M., Loubeau, M., Dai, X. M., Stanley, E. R., Randolph, G. J., and Merad, M. (2006). Langerhans cells arise from monocytes in vivo. Nat Immunol 7, 265-273.

Mende, I., Karsunky, H., Weissman, I. L., Engleman, E. G., and Merad, M. (2006). Flk2+ myeloid progenitors are the main source of Langerhans cells. Blood 107, 1383-1390.

Moore, Kateri, Ph.D.
Moore, Kateri A. and Ihor R. Lemischka, 2006, Stem Cells and Their Niches.  Science 311:1880-1885.

Hackney, Jason A. and Moore, Kateri A. Functional Genomics Approaches to Studying the Genetic Program of Stromal Cells, Methods in Molecular Medicine (M. Baron, Ed.) Humana Press 2005.

Moore, Kateri A.  2004, Recent Advances in Defining the Hematopoietic Stem Cell Niche.  Current Opinion in Hematology, 11:107-111.

Sokol, Sergei Y., Ph.D.
Ossipova, O., Tabler, J., Green, J. B., and Sokol, S. Y. (2007). PAR-1 specifies ciliated cells in vertebrate ectoderm downstream of aPKC. Development 134, 4297-4306.

Brott, B. K., and Sokol, S. Y. (2005). A vertebrate homolog of the cell cycle regulator Dbf4 is an inhibitor of Wnt signaling required for heart development. Dev Cell 8, 703-715.

Hikasa, H., and Sokol, S. Y. (2004). The involvement of Frodo in TCF-dependent signaling and neural tissue development. Development 131, 4725-4734.

Snoeck, Hans, M.D.- Ph.D.
Kumar, R., Langer, J. C., and Snoeck, H. W. (2006). Transforming growth factor-beta2 is involved in quantitative genetic variation in thymic involution. Blood 107, 1974-1979.

Langer, J. C., Kumar, R., and Snoeck, H. W. (2006). Age-related accumulation of a novel CD44 + CD25lowgammadelta T-cell population in hematopoietic organs of the mouse. J Gerontol A Biol Sci Med Sci 61, 568-571.

Takeshi, Sakurai, Ph.D.
Joseph D. Buxbaum, Lyudmila Georgieva, James J. Young, Christopher Plescia, Yuji Kajiwara, Yuhui Jiang, Valentina Moskvina, Nadine Norton, Tim Peirce, Hywel J. Williams, Nick J. Craddock, Liam Carroll, Gabriel Corfas, Kenneth L. Davis, Michael Owen, Sheila Harroch, Takeshi Sakurai, and Michael C. O’Donovan. Molecular dissection of NRG1-ERBB4 signaling implicates PTPRZ1 as a potential schizophrenia susceptibility gene. Molecular Psychiatry, in press.

Shin Yasuda, Hidekazu Tanaka, Hiroko Sugiura, Ko Okamura, Taiki Sakaguchi, Uyen Tran, Takako Takemiya, Akira Mizoguchi, Yoshiki Yagita, Takeshi Sakurai, Edward M. De Robertis, and Kanato Yamagata. Activity-induced protocadherin arcadlin regulates dendritic spine number by triggering N-cadherin endocytosis via TAO2b and p38 MAP kinases. Neuron, 56, 456-471, 2007

Scott E. Williams, Martin Grumet, David R. Colman, Mark Henkemeyer, Carol A. Mason, and Takeshi Sakurai. A role for Nr-CAM in the patterning of binocular visual pathways. Neuron, 50, 535-547, 2006

Taneja, Reshma, Ph.D.
Sun H, Ghaffari S, and Taneja R. (2007). bHLH-Orange transcription factors in development and cancer. Translational Oncogenomics 2: 105-118.

Sun H, Li L, Vercherat C, Gulbagci N, Acharjee S, Li J, Chung T-K, Thin T, and Taneja R. (2007). Stra13 regulates satellite cell activation by antagonizing Notch signaling. J. Cell Biol 177:647-57.

Thin T, Li L, Chung T-K, Sun H, and Taneja R (2007). Stra13 is induced by genotoxic stress and is required for ionizing radiation induced apoptosis. EMBO Reports 8:401-407.

Weinstein, Daniel, Ph.D.
Suri, C., Haremaki, T., and Weinstein, D. C. (2005). Xema, a foxi-class gene expressed in the gastrula stage Xenopus ectoderm, is required for the suppression of mesendoderm. Development 132, 2733-2742.

Weinstein, D.C. (2005).  Mesodermal differentiation: signal integration during development.  Science STKE tr 23.

Wilson, Patricia D., Ph.D.
Polgar, K., Burrow, C. R., Hyink, D. P., Fernandez, H., Thornton, K., Li, X., Gusella, G. L., and Wilson, P. D. (2005). Disruption of polycystin-1 function interferes with branching morphogenesis of the ureteric bud in developing mouse kidneys. Dev Biol 286, 16-30.

Wilson, P. D. (2004). Polycystic kidney disease: new understanding in the pathogenesis. Int J Biochem Cell Biol 36, 1868-1873.

Wolosin, Jose, Ph.D.
Budak, M. T., Alpdogan, O. S., Zhou, M., Lavker, R. M., Akinci, M. A., and Wolosin, J. M. (2005). Ocular surface epithelia contain ABCG2-dependent side population cells exhibiting features associated with stem cells. J Cell Sci 118, 1715-1724.

Wolosin, J. M., Budak, M. T., and Akinci, M. A. (2004). Ocular surface epithelial and stem cell development. Int J Dev Biol 48, 981-991.

Woo, Savio, Ph.D.
Chen, L., and Woo, S. L. (2005). Complete and persistent phenotypic correction of phenylketonuria in mice by site-specific genome integration of murine phenylalanine hydroxylase cDNA. Proc Natl Acad Sci U S A 102, 15581-15586.

Kubo, A., Shinozaki, K., Shannon, J. M., Kouskoff, V., Kennedy, M., Woo, S., Fehling, H. J., and Keller, G. (2004). Development of definitive endoderm from embryonic stem cells in culture. Development 131, 1651-1662.